(3-CARBOXYPROPYL)TRIPHENYLPHOSPHONIUM BROMIDE
(3-CARBOXYPROPYL)TRIPHENYLPHOSPHONIUM BROMIDE
CAS: 17857-14-6
Molecular Formula: C22H22BrO2P
(3-CARBOXYPROPYL)TRIPHENYLPHOSPHONIUM BROMIDE - Names and Identifiers
| Name | (3-CARBOXYPROPYL)TRIPHENYLPHOSPHONIUM BROMIDE |
| Synonyms | 3-Carbox 3-Carboxypropyltriphenylphosph 3-Carboxypropyltriphenylphosphonium bromide (3-CARBOXYPROPYL)TRIPHENYLPHOSPHONIUM BROMIDE (4-Hydroxy-4-oxobutyl)triphenylphosphonium bromide |
| CAS | 17857-14-6 |
| EINECS | 629-007-2 |
| InChI | InChI=1/C22H21O2P.BrH/c23-22(24)17-10-18-25(19-11-4-1-5-12-19,20-13-6-2-7-14-20)21-15-8-3-9-16-21;/h1-9,11-16H,10,17-18H2;1H |
| InChIKey | NKVJKVMGJABKHV-UHFFFAOYSA-N |
(3-CARBOXYPROPYL)TRIPHENYLPHOSPHONIUM BROMIDE - Physico-chemical Properties
| Molecular Formula | C22H22BrO2P |
| Molar Mass | 429.29 |
| Melting Point | 244-247°C(lit.) |
| Water Solubility | Soluble in water. soluble in ethanol. |
| Appearance | White powder particles |
| Color | White |
| BRN | 4173599 |
| Storage Condition | Inert atmosphere,Room Temperature |
| Sensitive | Hygroscopic |
| MDL | MFCD00274196 |
| Physical and Chemical Properties | Sensitivity: hydrogen WGK Germany:3 |
| Use | It is used as antimalarial agents, antimycobacterial agents,antifungal agents, inhibitors of protein tyrosine phosphatase. |
(3-CARBOXYPROPYL)TRIPHENYLPHOSPHONIUM BROMIDE - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. |
| WGK Germany | 3 |
| HS Code | 29319090 |
| Hazard Note | Irritant/Hygroscopic |
(3-CARBOXYPROPYL)TRIPHENYLPHOSPHONIUM BROMIDE - Reference Information
| Use | Used to prepare piperamide analogs as tissue protein deacetylase (HDAC) inhibitors, with anti-tumor activity; used to prepare benzoxabone as an anti-malarial agent; used to prepare methyl alkenyl quinolone as an anti-mycobacterial agent; used in the Sharpless epoxidation reaction, Taber cyclopropanation reaction, chemoselective reduction reaction and lithiation-boration-allylation sequence reaction to prepare monoplanide; used to prepare organotin compounds as antibacterial agents; used to prepare oleanolic acid derivatives as protein tyrosine phosphatase 1B Inhibitor, for negative regulation of the insulin pathway (a potential target for the treatment of diabetes and obesity); for the preparation of 11-oxoprostaglandin analogs with visual hypotensive effect |
Last Update：2024-04-09 20:49:11
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View History
(3-CARBOXYPROPYL)TRIPHENYLPHOSPHONIUM BROMIDE
Crocetane
silicon hydride
黃酮
boron mononi
Aliphatic alcohol dehydrogenase
IRON REDUCING AGENT
c7441
Catonic Gold Yellow X-GL
Diolane
Crocetane
silicon hydride
黃酮
boron mononi
Aliphatic alcohol dehydrogenase
IRON REDUCING AGENT
c7441
Catonic Gold Yellow X-GL
Diolane